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Not yet recruiting NCT07550907

The Impact of Surgical Procedures on Postoperative Outcomes in Cataract Phacoemulsification and Analysis of Related Factors

Conditions: Age-related Cataract

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

trial.available_in: БГ
Overview
The goal of this observational study is to evaluate the location of phacoemulsification tip measured by intraoperative OCT during cataract surgeries and its impact on early postoperative changes of cornea and visual acuity. The main question it aims to answer is: In patients with age-related cataracts undergoing phacoemulsification, does the location (supracapsular, iris-lens diaphragm, or endocapsular) of the phaco tip affect postoperative corneal changes and visual acuity at early postoperative stage? Eyes having phacoemulsification for cataracts will receive intraoperative OCT imaging to evaluate the location of the phaco tip during surgery, and corneal changes and visual acuity will be measured postoperatively.
Who can participate
Inclusion Criteria: * Age ≥ 50 years and ≤ 90 years * Diagnosis of unilateral/bilateral age-related cataract * Nuclear grade ≥2 in LOCSIII classification * Scheduled for cataract phacoemulsification combined with intraocular lens implantation * Pupil size ≥6mm after dilation * Corneal endothelial cell count ≥1500 cells/mm² Exclusion Criteria: * Diagnosis of severe systemic disease (e.g., severe hypertension or Alzheimer's disease) * History of ocular trauma or surgery * Presence of other ocular diseases (such as glaucoma, diabetic retinopathy, or high myopia) * Other ocular factors that may complicate the surgery (such as small pupil, shallow anterior chamber)
Interventions
cataract surgery
PROCEDURE
Locations

Location information is not available.

Technical details
Status
Not yet recruiting
Study type
OBSERVATIONAL
Sex
Male and female
Minimum age
50 Years
Maximum age
90 Years
Healthy volunteers
No
Start date
30.04.2026
Completion date
30.06.2027
Registry ID
NCT07550907
Source
clinicaltrials.gov
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