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Not yet recruiting Not applicable NCT07550738

Effect of Pressure-Controlled Volume Guaranteed Versus Volume-Controlled Ventilation Modes on Hemodynamic Outcomes e.g ( SV, CO ) and Respiratory Mechanics During Laparoscopic Abdominal Cancer Surgeries With Exaggerated Trendelenberg Postion

No applicable phase (e.g. observational)
Conditions: PCV-VG Versus VCV Ventilation Mode Effects on Hemodynamics

Sponsor: Assiut University

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Overview
The primary outcome is to compare the hemodynamic outcomes ( e.g SV , CO and CI ) using The ICON of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated trendelenburg position. And the secondary outcomes is to compare the respiratory effects ( e.g atelectasis development , plateau pressure(Pplat) , peak inspiratory pressure(PIP) , dyn. compliance and postoperative inflammatory indicators e.g CRP and WBCs ) of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated trendelenburg position.
Who can participate
Inclusion Criteria: 1 - All patients who will be scheduled for elective laparoscopic abdominal cancer surgeries 2- patients aged 20-80 years 3- patients have an American Society of Anesthesiologists (ASA) physical status I-II Exclusion Criteria: 1 - Patients with severe systemic disease (history of myocardial infarction, chronic obstructive, or restrictive lung disease) 2- Obese patients (BMI \> 30) 3- patients with neurologic or neuromuscular diseases.
Interventions
electrical cardiometry ('ICON CARDIOTRONIC, OSYPKA MEDICAL') , Lung ultrasonography (LUS) for atelectasis
DIAGNOSTIC_TEST
Locations 1
Egypt (1)
South Egypt cancer institute , Assiut university
Asyut
Saif eldeen Gamal Khalaf, Assistant lecturer
Technical details
Status
Not yet recruiting
Phase
Not applicable
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
20 Years
Maximum age
80 Years
Healthy volunteers
No
Start date
01.05.2026
Completion date
01.06.2027
Registry ID
NCT07550738
Source
clinicaltrials.gov
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