A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease

This research is studying the use of a new type of standing desk in a small number of people to learn about the user experience for people with Parkinson's disease. 12 4-hour sessions will be performed to test the primary hypothesis that dynamic standing improves gait function compared to static standing and control sitting. This study has 2 phases. Phase 1 will be an open-label study and Phase 2 will be an in-lab randomized controlled trial pilot study. This is phase 1 of the study.

For phase 1, participants will attend up to 12 4-hour sessions using the dynamic standing desk. In addition to these sessions, there will be a clinical assessment at baseline and an outcome session (endpoint assessments). In total, there will be up to 14 sessions per participant. All sessions need to be completed within 6 weeks. At the baseline session, clinical measurements will be collected. These measures will be repeated in the outcome session.

Inclusion Criteria: * Diagnosis of Parkinson's Disease Exclusion Criteria: * Inability to stand or walk without an assistive device * History of symptoms in stance that preclude safe and comfortable participation, such as dizziness and lightheadedness, orthostasis, severe symptomatic leg or back musculoskeletal pain, or medication side effects * Any other history of medical or psychiatric comorbidity, precluding safe participation in the project. * History of symptomatic cardiovascular or pulmonary disease * History of active rheumatic arthritis * History of stroke or other neurologic conditions with significant residual sensorimotor deficits * History of disabling chronic pain syndrome requiring narcotic analgesics * Evidence of dementia (Mini Mental State Exam (or Montreal Cognitive Assessment test) \<24 and significant impairment in activities of daily living) * Venous ulcerative stasis or severe varicosities. * Pregnancy as determined by urine pregnancy test prior to DXA procedure in women of childbearing potential.