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Recruiting Not applicable NCT07485738

The Relationship Between Blood Flow Readings During Surgery and How Well the Graft Stays Open and How Patients Recover Afterward in Coronary Artery Bypass Graft Surgery

No applicable phase (e.g. observational)
Conditions: CABG Graft Integrity CABG Blood Flow Transit-time Flow Measurement Heart Disease

Sponsor: Weill Medical College of Cornell University

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Overview
The purpose of this study is to learn more about a tool called Transit-Time Flow Measurement (TTFM). TTFM uses sound waves during surgery to check how well blood is flowing through blood vessels. This helps doctors see if the blood flow is good during coronary artery bypass grafting (CABG), which is a type of heart surgery
Description
The SMARTFLOW:Patency trial is designed to fill this critical evidence gap by evaluating the impact of CABG graft quality assessment by TTFM on clinical outcomes in a large randomized cohort. SMARTFLOW:Patency will evaluate the impact of CABG graft quality assessment by TTFM on graft patency.
Who can participate
Inclusion Criteria: 1. Age \>18 years 2. First-time, non-emergent isolated multivessel CABG through median sternotomy 3. Willing and able to provide written informed consent and comply with all study procedures, including QOL questionnaires Exclusion Criteria: 1. Reoperation 2. Emergency procedures 3. Combined CABG + other cardiac or non-cardiac surgery 4. Isolated single vessel CABG 5. Minimally invasive CABG 6. Inability to undergo coronary computed tomographic angiography (CCTA) 7. Unable to provide written informed consent or comply with all the study procedures.
Interventions
Transit-Time Flow Measurement (TTFM)
DEVICE
Locations 1
United States (1)
Weill Cornell Medicine/NewYork Presbyterian Hospital
New York , New York
Technical details
Status
Recruiting
Phase
Not applicable
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Healthy volunteers
No
Start date
30.03.2026
Completion date
01.03.2032
Registry ID
NCT07485738
Source
clinicaltrials.gov
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