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Набира участници Фаза 2 NCT07395687

A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity

Фаза 2 – изследване на ефективността и дозировката
Заболявания: Overweight Obesity

Спонсор: Novo Nordisk A/S

Налично на: БГ
Обобщение
The purpose of this clinical study is to find out if UBT251 is safe and effective for treating people who are living with overweight or obesity. Participants will get either UBT251 (the treatment being tested) or Placebo (a treatment that has no active medicine in it), which treatment participants get is decided by chance.
Кой може да участва
Inclusion Criteria: 1. Male or female (sex at birth). 2. For Part C: Japanese, Chinese or non-Asian participants (all self-reported): * For Japanese participants: both parents of Japanese descent. * For Chinese participants: both parents of Chinese descent. * For non-Asian participants: both parents of non-Asian descent (non-Asian is defined as of countries outside of Asia). 3. Age at the time of signing the informed consent: 1. For Part A: 18-55 years (both inclusive) 2. For Part B: 18-65 years (both inclusive) 3. For Part C: 18-55 years (both inclusive). 4. BMI at screening (overweight and obesity should be due to excess adipose tissue, as judged by the investigator): 1. For Part A: 27.0-39.9 kilogram per meter square (kg/m\^2) (both inclusive) 2. For Part B: 30.0-50.0 kg/m\^2 (both inclusive) 3. For Part C: 24-34.9 kg/m\^2 (both inclusive) 5. Considered eligible based on the medical history, physical examination, and the results of vital signs, electrocardiogram (ECG), and clinical laboratory tests performed during the screening visit, as judged by the investigator. Exclusion Criteria: 1. Known or suspected hypersensitivity to study intervention(s) or related products. 2. Treatment with any marketed product containing compounds with glucagon-like peptide 1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) or glucagon receptor agonism within 90 days before screening. 3. Any condition, unwillingness or inability, which in the investigator's opinion might jeopardise the participant's safety or compliance with the protocol.
Интервенции
UBT251
DRUG
Placebo
DRUG
Места на провеждане 3
Канада (1)
Altasciences Clinical Company, Inc
Montreal , Quebec
САЩ (2)
Altasciences Clinical LA, Inc.
Cypress , California
Altasciences Clinical Kansas, Inc.
Overland Park , Kansas
Технически детайли
Статус
Набира участници
Фаза
Фаза 2
Вид изследване
INTERVENTIONAL
Пол
Мъже и жени
Минимална възраст
18 Years
Максимална възраст
65 Years
Здрави доброволци
Не
Начална дата
02.02.2026
Крайна дата
18.02.2027
Регистрационен номер
NCT07395687
Източник
clinicaltrials.gov
Запитване за медицински туризъм

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