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Not yet recruiting Not applicable NCT07389226

The Effect of Apple Cider Vinegar Supplementation on 24-hour Urine Chemistry in Adults

No applicable phase (e.g. observational)
Conditions: Kidney Stones Urine Specimen Collection

Sponsor: University of Chicago

trial.available_in: БГ
Overview
This is a single-center prospective cohort study to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.
Description
The primary objective of this study is to determine whether a two-week course of daily ACV supplementation significantly changes an individual's urine chemistry. The investigators will study this in healthy individuals and individuals with kidney stones.
Who can participate
Inclusion Criteria: * Controls: Adults above the age of 18. * Kidney stone patients: Adults above the age of 18. * History of majority (\>50%) calcium oxalate kidney stones Exclusion Criteria: * Anyone with a history of calcium phosphate stones (\>50% calcium phosphate), uric acid stones, struvite stones, recent urinary tract instrumentation (\<30 days), or recurrent urinary tract infections. * Any individual who has had ACV outside of normal consumption in the prior month will be excluded. * Any individual who has a history of a negative reaction (increased acid reflux, allergy) to ACV will also be excluded. * Any individual with chronic kidney disease, underlying acid base disorder will also be excluded.
Interventions
Apple Cider Vinegar
DIETARY_SUPPLEMENT
Locations 1
United States (1)
The University of Chicago
Chicago , Illinois
Technical details
Status
Not yet recruiting
Phase
Not applicable
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Healthy volunteers
No
Start date
01.05.2026
Completion date
01.02.2028
Registry ID
NCT07389226
Source
clinicaltrials.gov
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