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Набира участници Фаза 1 NCT07342114

A Dose-Escalation Study of RO7875913 in Healthy Participants

Фаза 1 – тестване на безопасността при малка група хора
Заболявания: Healthy Volunteers

Спонсор: Genentech, Inc.

Налично на: БГ
Обобщение
The purpose of this study is to evaluate the safety, pharmacokinetics, and pharmacodynamics of RO7875913 in healthy participants.
Кой може да участва
Inclusion Criteria: * Agreement to adhere to the contraception requirements * Body weight \> 40 kilogram (kg) with a body mass index of 18-30 kg per meter square (kg/m\^2) Exclusion Criteria: * Positive test result for hepatitis B surface antigen, hepatitis C virus (HCV), or human immunodeficiency virus (HIV) antibody screen * History of any malignancy * Major surgical procedure within 28 days prior to initiation of study treatment, or anticipation of need for a major surgical procedure during the study * History or clinical manifestations of significant metabolic, hepatic, renal, pulmonary, cardiovascular, hematologic, gastrointestinal, urologic, neurologic, or psychiatric disorders * Known allergy or hypersensitivity to any component of the RO7875913 formulation * Treatment with investigational biologic therapy (or blinded comparator) within 90 days or 5 drug elimination half-lives, whichever is longer, prior to initiation of study drug * Treatment with investigational non-biologic therapy (or blinded comparator) within 28 days or 5 drug elimination half-lives, whichever is longer, prior to initiation of study drug * Treatment with any immunosuppressive medication within 28 days or 5 drug elimination half-lives, whichever is longer, prior to initiation of study drug
Места на провеждане 1
New Zealand (1)
New Zealand Clinical Research - Christchurch
Christchurch , Canterbury
Технически детайли
Статус
Набира участници
Фаза
Фаза 1
Вид изследване
INTERVENTIONAL
Пол
Мъже и жени
Минимална възраст
18 Years
Максимална възраст
65 Years
Здрави доброволци
Не
Начална дата
11.03.2026
Крайна дата
31.12.2026
Регистрационен номер
NCT07342114
Източник
anzctr
Запитване за медицински туризъм

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