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Recruiting Not applicable NCT06943586

Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing

No applicable phase (e.g. observational)
Conditions: Stroke Transient Ischemic Attack (TIA)

Sponsor: University of Alabama at Birmingham

trial.available_in: БГ
Overview
The purpose of this research study is to explore whether genetic testing can offer a personalized and timely approach to assist physicians in making more informed medication decisions for stroke or high-risk transient ischemic attack (TIA) patients during their hospital stay.
Description
This is a pilot clinical trial for feasibility
Who can participate
Inclusion Criteria: * Patients 18-89 years of age * admitted to University of Alabama at Birmingham (UAB) main hospital with symptoms or signs of minor ischemic stroke, or high risk TIA * eligible to receive dual antiplatelet load (presented to the hospital within 66 hours of last known well) Exclusion Criteria: * diagnosis of atrial fibrillation, valvular heart disease, index stroke due to known hypercoagulability (subset of other determined etiology) or large vessel disease (culprit vessel stenosis of ≥50%) * prescribed anticoagulation prior to stroke * treated with intravenous thrombolysis * treated with mechanical thrombectomy * missing NIH Stroke Scale score
Interventions
CYP2C19 Genotype Guided DAPT (dual antiplatelet therapy)
GENETIC
Locations 1
United States (1)
University of Alabama at Birmingham
Birmingham , Alabama
Technical details
Status
Recruiting
Phase
Not applicable
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Maximum age
89 Years
Healthy volunteers
No
Start date
09.04.2025
Completion date
01.04.2029
Registry ID
NCT06943586
Source
clinicaltrials.gov
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