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Активно (без набиране) Фаза 2 NCT06925750

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-031/LIGHTRAY EXTENSION)

Фаза 2 – изследване на ефективността и дозировката
Заболявания: Pulmonary Arterial Hypertension

Спонсор: Merck Sharp & Dohme LLC

Налично на: БГ
Обобщение
Researchers are looking for other ways to treat pulmonary arterial hypertension (PAH). Sotatercept is a study medicine that is designed to treat PAH. A past study, MK-7962-024 (LIGHTRAY) (NCT06664801), learned about the safety and effects of sotatercept in people with PAH. One of the goals of that study was to learn about sotatercept when given at a dose (amount) based on the weight range a person is in (weight-banded doses) compared to when given based on a person's exact weight. This is an extension study, which means people who took part in MK-7962-024 (LIGHTRAY) may be able to join this study. In this extension study, people will get weight-banded doses of sotatercept. The main goal of this study is to learn about the safety of weight-banded doses of sotatercept and if people tolerate it over a longer period of time.
Кой може да участва
Inclusion Criteria: The main inclusion criteria include but are not limited to the following: * Has completed the treatment period of study MK-7962-024 (LIGHTRAY) (including Visit 11) on study intervention, did not discontinue study intervention, and is able to safely enroll into MK-7962-031 (LIGHTRAY EXTENSION) * Has not started treatment with commercially available sotatercept Exclusion Criteria: The main exclusion criteria include but are not limited to the following: \- Has current exposure or is planning to begin treatment with an activin signaling inhibitor (other than sotatercept)
Места на провеждане 19
Argentina (1)
Centro Medico Capital ( Site 0002)
La Plata , Buenos Aires
Австралия (1)
Royal Prince Alfred Hospital ( Site 0103)
Camperdown , New South Wales
Канада (1)
IUCPQ ( Site 0208)
Québec , Quebec
Китай (1)
Guangdong Provincial People's Hospital-Cardiology ( Site 2000)
Guangzhou , Guangdong
Colombia (1)
Clinica Colsanitas - Sede Reina Sofia ( Site 0303)
Bogotá , Bogota D.C.
Чехия (1)
Vseobecna fakultni nemocnice v Praze ( Site 0400)
Prague , Praha 2
Франция (1)
CHU Bordeaux Haut-Leveque ( Site 0501)
Pessac , Aquitaine
Унгария (1)
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Családorvosi Intézet és Rendelő ( Site 0704)
Szeged , Csongrád megye
Израел (1)
Rambam Health Care Campus ( Site 0802)
Haifa
Италия (1)
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico ( Site 0902)
Milan , Lombardy
Япония (1)
Nagoya University Hospital ( Site 2102)
Nagoya , Aichi-ken
Нидерландия (1)
Radboud University Medical Center ( Site 1001)
Nijmegen , Gelderland
Сингапур (1)
National University Heart Centre, Singapore ( Site 1200)
Singapore , Central Singapore
Южна Корея (1)
Chonnam National University Hospital ( Site 1304)
Gwangju , Kwangju-Kwangyokshi
Испания (1)
Hospital Universitari Son Espases ( Site 1412)
Palma , Balearic Islands
Taiwan (1)
National Cheng Kung University Hospital ( Site 1501)
Tainan
Тайланд (1)
Faculty of Medicine Siriraj Hospital ( Site 1600)
Bangkoknoi , Bangkok
Великобритания (1)
Royal Papworth Hospital ( Site 1802)
Cambridge , Cambridgeshire
САЩ (1)
University of Colorado Anschutz Medical Campus-University of Colorado Hospital Cardiac and Vascular ( Site 1930)
Aurora , Colorado
Технически детайли
Статус
Активно (без набиране)
Фаза
Фаза 2
Вид изследване
INTERVENTIONAL
Пол
Мъже и жени
Минимална възраст
18 Years
Здрави доброволци
Не
Начална дата
12.05.2025
Крайна дата
16.06.2028
Регистрационен номер
NCT06925750
Източник
anzctr
Запитване за медицински туризъм

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