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Recruiting NCT06830759

Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma

Conditions: Diffuse Large B-cell Lymphoma Follicular Lymphoma

Sponsor: AbbVie

trial.available_in: БГ
Overview
Diffuse large B-cell lymphoma (DLBCL) is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections) and the most common type of non-Hodgkin lymphoma. Follicular Lymphoma (FL) is a slow-growing type of non-Hodgkin lymphoma. The purpose of this study is to assess the real-world effectiveness of subcutaneous epcoritamab in adult participants with advanced DLBCL and FL. Epcoritamab is an investigational drug being developed for treating participants with DLBCL and FL. Approximately 700 participants will be enrolled in approximately 80 sites across 12-20 countries globally. Participants will receive epcoritamab as prescribed by their physician in accordance with local country label. Participants will be followed for up to 3 years. There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.
Who can participate
Inclusion Criteria: * Participants who are scheduled to be treated with epcoritamab for Treatment after two or more prior lines of therapy 3L+ diffuse large B-cell lymphoma ((D)LBCL) or 3L+ Follicular lymphoma (FL). * Treatment with epcoritamab should be administered in accordance with the approved local label in the participating country. * The decision to treat the participant should have been made by the clinician prior to, and independently of any decision to approach the participant to participate in this study. Exclusion Criteria: * Any condition included in the contraindications section of the approved local epcoritamab label in the participating country. * Participation in a concurrent interventional clinical trial (not including non-interventional/ observational study, PMOS, or registry participation) from enrollment and throughout the study.
Locations 12
Argentina (1)
Hospital Britanico de Buenos Aires /ID# 274419
Ciudad Autonoma de Buenos Aire , Buenos Aires
Australia (1)
Nepean Cancer Centre, Nepean Hospital /ID# 277782
Kingswood , New South Wales
Belgium (1)
Algemeen Ziekenhuis klina /ID# 273405
Brasschaat , Antwerpen
Bulgaria (1)
Umhat Sveti Ivan Rilsky /ID# 274898
Sofiya , Sofia
Canada (1)
Cross Cancer Institute /ID# 271504
Edmonton , Alberta
Greece (1)
Agios Andreas Hospital Patras /ID# 273629
Pátrai , Achaia
Site Coordinator
Israel (1)
Tel Aviv Sourasky Medical Center /ID# 271615
Tel Aviv , Tel Aviv
Italy (1)
IRCCS Ospedale San Raffaele /ID# 274789
Milan , Milano
Mexico (1)
Hematologica Alta Especialidad /ID# 275279
Huixquilucan de Degollado
Portugal (1)
Unidade Local de Saude de Coimbra, EPE /ID# 272720
Coimbra
Spain (1)
Complejo Hospitalario Universitario A Coruña /ID# 272040
A Coruña , A Coruna
United Kingdom (1)
Milton Keynes Hospital /ID# 272817
Milton Keynes , Buckinghamshire
Technical details
Status
Recruiting
Study type
OBSERVATIONAL
Sex
Male and female
Minimum age
18 Years
Healthy volunteers
No
Start date
28.03.2025
Completion date
01.09.2031
Registry ID
NCT06830759
Source
anzctr
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