Език: EN EN
← Назад към резултатите
Предстои набиране Не е приложимо NCT06738589

The Inflate Study; Defining the Soft Palate in the Upper Airway Flow Pathway

Не е приложима фаза (напр. обсервационно)
Заболявания: Focus of the Study is the Anatomy of the Soft Palate Non-invasive Ventilation

Спонсор: Fisher and Paykel Healthcare

Налично на: БГ
Обобщение
The goal of this clinical trial is to understand the impact of the size and shape of the soft palate on gas airflow in the upper airway in healthy volunteers. Utilizing Magnetic Resonance Imaging (MRI), this study aims to investigate: * How does soft palate anatomy change in different body positions? * What is the impact of positive pressure therapy, in the form of non-invasive ventilation (NIV) on soft palate anatomy? Researchers will compare MRI data without positive pressure to with positive pressure imaging to see if the addition of positive pressure impacts the size and shape of the soft palate. Researchers will also utilize measures of upper airway resistance to assess the impact of soft palate anatomy of airflow dynamics. Participants will be asked to: * Lie inside an MRI scanner for up to 90 minutes (including breaks), in different body positions * Undergo NIV therapy for 5-10 minutes while breathing normally inside an MRI scanner * Have their upper airway resistance measured, in different body positions
Кой може да участва
Inclusion Criteria: * Healthy adults aged 18+ * Willing and able to consent to the study Exclusion Criteria: * Contraindications for MRI (such as metal implants) * Contraindications for NIV (such as pneumothorax) * No history of lung or upper airway disease * Claustrophobia * Symptoms of a cold, flu, or significant congestion, within the last 3 days * Self-reported confirmed or suspected pregnancy * Palatal abnormalities or previous upper airway surgery (such as cleft palate and/or UPPP) * Prior major head or neck surgery with or without irradiation (such as radiotherapy of cutaneous cancers, robotic surgery for an oropharyngeal cancer)
Места на провеждане 1
New Zealand (1)
University of Auckland
Auckland
Технически детайли
Статус
Предстои набиране
Фаза
Не е приложимо
Вид изследване
INTERVENTIONAL
Пол
Мъже и жени
Минимална възраст
18 Years
Здрави доброволци
Не
Начална дата
25.03.2025
Крайна дата
01.08.2027
Регистрационен номер
NCT06738589
Източник
anzctr
Запитване за медицински туризъм

Информацията е извлечена автоматично от ClinicalTrials.gov. Консултирайте се с вашия лекар преди да предприемете действия.