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Not yet recruiting NCT06527079

Evaluation of Clinical Decision Support in Opioid Tapering

Conditions: Medication Abuse Harm Reduction Opioid Use Disorder Opioid Prescribing Opioid Overdose Prevention

Sponsor: University of Colorado, Denver

trial.available_in: БГ
Overview
The 2022 Center for Disease Control and Prevention (CDC) clinical practice guideline for prescribing opioids for pain recommends that when tapering a patient's opioid dose, doses should be decreased at a slow rate to reduce the risk of withdrawal symptoms, overdose, and to promote tolerance of the tapering. This project will evaluate a clinical decision support (CDS) tool in the form of a clinical care pathway that gives providers information, recommendations, and educational material on strategies for opioid tapering. Primary care providers will be randomized at the clinic location to a control arm or intervention arm. The control arm will have the clinical care pathway available, but will not be reminded of the pathway when tapering a patient. The intervention arm will receive a nudge when prescribing a tapering opioid strategy to a patient to use the clinical care pathway. The rate of opioid tapering in line with CDC guidelines will be examined as well as long-term patient outcomes of opioid overdose or poisoning using existing patient health records. The study period will be approximately 18 months.
Who can participate
Inclusion Criteria: Primary care patients being tapered from an opioid. Tapering patients: * Have an active opioid prescription for more than 3 months and * Prescribed more than 90 morphine milligram equivalents (MME) per day or * Co-prescribed an opioid and benzodiazepine or * Received a reduction in opioid dosage by more than 5% MME per day Exclusion Criteria: * Patients \<12 and \>89 * Patients with active cancer diagnosis in last 1 year * Patients with hospice care/palliative care order * Patients with sickle cell disease diagnosis
Interventions
Opioid Tapering Pathway Clinical Decision Support (CDS)
OTHER
Locations

Location information is not available.

Technical details
Status
Not yet recruiting
Study type
OBSERVATIONAL
Sex
Male and female
Minimum age
12 Years
Maximum age
89 Years
Healthy volunteers
No
Start date
01.08.2026
Completion date
01.06.2027
Registry ID
NCT06527079
Source
clinicaltrials.gov
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