Cardiac Amyloidosis pRevaleNce of in OLDer Subjects Affected by Heart Failure
Заболявания:
Cardiac Amyloidosis
Спонсор: Gérond'if
Налично на:
БГ
Обобщение
Tne aim purpose of this observational, multicentre and propective study is to determine the prevalence of cardiac amyloidosis in geriatric patients aged 80 years and older hospitalized within the last 12 months for heart failure with left ventricular hypertrophy (septum ≥ 12 mm) on echocardiography
Описание
Patients recruitment will be curry out in 31 geriatric or cardiologic centres.
Patients will be recruited for 24 months. Each patient will participate in the study for 12 months (baseline visit, follow-up phone calls every 3 months up to 12 months i.e., at 3, 6, 9 and 12 months).
The following data will be collected at teh baseline visit: Medical history, demography, clinical data, frailty status assessed by Fried, Triage Risk Screening Tool (TRST), triggers for cardiac decompensation, biological examination, genetic testing, echocardiographic data and other data.
Bone scanning with 99mTc-DPD or 99mTc-HMDP (early or late time with SPECT will be done during hospitalization or after discharge depending on availability at the imaging centre.
The results of each examination will be evaluated to establish the existence and degree of fixation in the myocardium and to determine its distribution.
Follow-up phone s will be conducted every 3 months up to 12 months to collect hospitalizations for heart failure, hospitalizations for other cardio-vascular events, hospitalizations for non-cardiac events, admission to nursing homes or long-term care (LTC) facilities and death
Кой може да участва
Inclusion Criteria:
* Aged ≥ 80 years
* Hospitalised for decompensation of heart failure in the last 12 months
* Subjects with hypertrophy of the septum or left ventricle at cardiac echography (defined as ≥ 12 mm)
* Subjects able to undergo a bone scintigraphy scan
* Subjects willing to participate
Exclusion Criteria:
* Subjects refusing to participate
* Subjects admitted to palliative care unit.
* Subjects under guardianship
* Subjects with a definite diagnosis of cardiac amyloidosis
Места на провеждане
36
Франция (36)
CHU Amiens Picardie
Amiens
CHU Angers
Angers
CHU Bordeaux
Bordeaux
Ambroise Paré Hospital
Boulogne-Billancourt , Île-de-France Region
Centre Hospitalier de Carcassonne
Carcassonne
Centre Hospitalier Intercommunal de Castres-Mazamet
БГ
EN