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By invitation only NCT06138808

5-SENSE Score Validation Study

Conditions: Epilepsy Intractable

Sponsor: Duke University

trial.available_in: БГ
Overview
The purpose of this study is to assess how well a new scoring system called the 5-SENSE score can predict where seizures start in the brain using Stereoelectroencephalography (SEEG). The 5-SENSE Score is a 5-point score based on routine presurgical work-up, designed to assist in predicting whether SEEG can identify a focal seizure onset zone, thereby sparing patients the risk of undergoing this invasive diagnostic procedure.
Who can participate
Inclusion Criteria: * patients aged 15 years or older in whom no direct surgical approach can be offered and who are discussed in the multidisciplinary team discussion * availability of complete non-invasive presurgical work-up (including high-resolution MRI according to the in-center epilepsy protocol, video-telemetry with the recording of a minimum of one habitual clinic and EEG seizure, available as original files for review) Exclusion Criteria: * no telemetry/scalp EEG in center * no protocol MRI in center * subdural/GRID electrodes
Locations 10
Australia (1)
Monash University
Melbourne , Victoria
Canada (1)
Dalhousie Universiry and Hospital
Dalhousie , Nova Scotia
Czech Republic (1)
Departmet of Neurology, Masaryk University Brno
Brno
Denmark (1)
Danish Epilepsy Centre, Aarhus Universitets Hospital
Aarhus
France (1)
Grenoble Institute of Neurosciences, Centre Hospitalier Universitaire Grenoble Alpes
Grenoble
Japan (1)
University School of Medicine Kyoto
Kyoto
Romania (1)
"Carol Davila" University of Medicine and Pharmacy
Bucharest
Spain (1)
Hospital Universitario y Politecnico La Fe
Valencia
Switzerland (1)
Department of Clinical Neurosciences chez CHUV; Centre Hospitalier Universitaire Vaudois
Lausanne
United States (1)
University of Florida College of Medicine
Gainesville , Florida
Technical details
Status
By invitation only
Study type
OBSERVATIONAL
Sex
Male and female
Minimum age
15 Years
Healthy volunteers
No
Start date
09.01.2024
Completion date
01.06.2027
Registry ID
NCT06138808
Source
anzctr
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