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Active (not recruiting) NCT03839784

Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient

Conditions: Cognitive Decline Cognitive Change Cognitive Impairment Postoperative Delirium Anesthesia; Reaction Anesthesia; Adverse Effect

Sponsor: Stanford University

trial.available_in: БГ
Overview
The research team is creating a foundational infrastructure in order to develop a precision medicine approach for geriatric patients who require surgery with anesthesia. The team plans to build the first of its kind comprehensive database of demographic and risk factor questionnaire responses, biobanked blood specimens, intraoperative electroencephalography (EEG), and inclusive cognitive testing throughout patient interaction starting at the preop appointment until a year later. This will be used to create a predictive model of periooperative neurocognitive disorders.
Who can participate
Inclusion Criteria: * At least 65 years old (inclusive) * Non cardiac general elective surgery * General anesthesia is expected for 2+ hours Exclusion Criteria: * Alzheimer's * Dementia * Parkinson's * History of neurodegenerative diseases * Medication for depression (ie. Benzodiazepines) * Alcoholism * Discretion of PI
Interventions
Neurocognition Interventions
COMBINATION_PRODUCT
Locations 1
United States (1)
Stanford Medical Center
Stanford , California
Technical details
Status
Active (not recruiting)
Study type
OBSERVATIONAL
Sex
Male and female
Minimum age
65 Years
Healthy volunteers
No
Start date
01.09.2020
Completion date
30.08.2030
Registry ID
NCT03839784
Source
clinicaltrials.gov
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