Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility
Не е приложима фаза (напр. обсервационно)
Заболявания:
Endometriosis
Infertility
Спонсор: University Hospital, Lille
Налично на:
БГ
Обобщение
The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility. Patients will be randomized in two parallel-groups; one group underwent complete surgery of colorectal DIE prior to ART and the other group underwent ART alone (ratio 1:1)
Кой може да участва
Inclusion Criteria:
* Primary and secondary infertility
* Indication for IVF
* Persistent pain related to endometriosis with analgesic medical treatment failure
* Persistent pain including at least one of the following digestive symptoms related to endometriosis: Dyschesia / Sub-occlusive syndrome / Rectal bleeding / Painful defecation
* Colorectal deep infiltrating endometriosis : Whatever lesion size / With at least rectal serosal involvement / Confirmed by MRI and 1 different investigation: vaginal ultrasound echography or coloscopic CT scan or rectal endoscope ultrasound
* Eligible for DIE surgery
Exclusion Criteria:
* Contraindication to pregnancy or to IVF
* Viral risk
* Previous IVF cycle(s)
* Previous colorectal surgery
* Need of myomectomy during surgery
* The use of oocytes donor