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Recruiting Not applicable NCT02948972

Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility

No applicable phase (e.g. observational)
Conditions: Endometriosis Infertility

Sponsor: University Hospital, Lille

trial.available_in: БГ
Overview
The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility. Patients will be randomized in two parallel-groups; one group underwent complete surgery of colorectal DIE prior to ART and the other group underwent ART alone (ratio 1:1)
Who can participate
Inclusion Criteria: * Primary and secondary infertility * Indication for IVF * Persistent pain related to endometriosis with analgesic medical treatment failure * Persistent pain including at least one of the following digestive symptoms related to endometriosis: Dyschesia / Sub-occlusive syndrome / Rectal bleeding / Painful defecation * Colorectal deep infiltrating endometriosis : Whatever lesion size / With at least rectal serosal involvement / Confirmed by MRI and 1 different investigation: vaginal ultrasound echography or coloscopic CT scan or rectal endoscope ultrasound * Eligible for DIE surgery Exclusion Criteria: * Contraindication to pregnancy or to IVF * Viral risk * Previous IVF cycle(s) * Previous colorectal surgery * Need of myomectomy during surgery * The use of oocytes donor
Interventions
complete surgery
PROCEDURE
In vitro fertilization without surgery
PROCEDURE
Locations 5
France (5)
CHU
Clermont-Ferrand
Hôpital Jeanne de Flandres, CHRU
Lille
AP-HP, Hôpital Tenon
Paris
CHU
Poissy
CHU
Rouen
Technical details
Status
Recruiting
Phase
Not applicable
Study type
INTERVENTIONAL
Sex
Female only
Minimum age
18 Years
Maximum age
38 Years
Healthy volunteers
No
Start date
17.11.2016
Completion date
01.05.2026
Registry ID
NCT02948972
Source
clinicaltrials.gov
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