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Active (not recruiting) Phase 4 2025-521621-33-00

Long-term Safety Outcomes in Patients Treated With Replimune Oncolytic Immunotherapy Products

Phase 4 – monitoring after market approval
Conditions: Metastatic Melanoma Advanced solid tumors Hepatocellular Carcinoma Melanoma

Sponsor: Replimune Group Inc.

trial.available_in: БГ
Overview
Trial status: Authorised Evaluation of delayed adverse event(s) will be based on the occurrence of: New malignancy(ies); New incidence or exacerbation of a pre-existing neurologic disorder​; New incidence or exacerbation of a pre-existing rheumatologic or other autoimmune disorder; New incidence of a hematologic disorder; New incidence of infection related to RPx​, New herpetic infection and presence of RPx detected in samples collected from herpetic lesions
Who can participate
Age group: 18-64 years, 65+ years Gender: Female, Male Target enrollment: 41 participants
Interventions
Vusolimogene oderparepvec
Drug
Vusolimogene oderparepvec
Drug
Vusolimogene oderparepvec
Drug
RP3
Drug
RP2
Drug
RP2
Drug
Vusolimogene oderparepvec
Drug
Vusolimogene oderparepvec
Drug
RP2
Drug
RP3
Drug
RP3
Drug
Locations 5
France (1)
Germany (1)
Greece (1)
Poland (1)
Spain (1)
Technical details
Status
Active (not recruiting)
Phase
Phase 4
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Healthy volunteers
No
Start date
09.02.2026
Registry ID
2025-521621-33-00
Source
euclinicaltrials.eu
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